BDBM50055282 2-Methyl-isothiourea::CHEMBL356703

SMILES: CSC(N)=N

InChI Key: InChIKey=SDDKIZNHOCEXTF-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50055282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50055282 (2-Methyl-isothiourea | CHEMBL356703) Show SMILES CSC(N)=N Show InChI InChI=1S/C2H6N2S/c1-5-2(3)4/h1H3,(H3,3,4)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrulline				Bioorg Med Chem 16: 6193-206 (2008) Article DOI: 10.1016/j.bmc.2008.04.036 BindingDB Entry DOI: 10.7270/Q2611040
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50055282 (2-Methyl-isothiourea | CHEMBL356703) Show SMILES CSC(N)=N Show InChI InChI=1S/C2H6N2S/c1-5-2(3)4/h1H3,(H3,3,4)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Medical School Curated by ChEMBL					Assay Description The compound was evaluated for the inhibitory potencies using human Inducible nitric oxide synthase (hiNOS)				J Med Chem 39: 5110-8 (1997) Article DOI: 10.1021/jm960481q BindingDB Entry DOI: 10.7270/Q29W0DKZ
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50055282 (2-Methyl-isothiourea | CHEMBL356703) Show SMILES CSC(N)=N Show InChI InChI=1S/C2H6N2S/c1-5-2(3)4/h1H3,(H3,3,4)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Medical School Curated by ChEMBL					Assay Description The compound was evaluated for the inhibitory potencies using human Endothelial nitric oxide synthase				J Med Chem 39: 5110-8 (1997) Article DOI: 10.1021/jm960481q BindingDB Entry DOI: 10.7270/Q29W0DKZ
					More data for this Ligand-Target Pair