BDBM50055472 CHEMBL356173::[4-(3-Ethoxy-pyridin-2-yl)-piperazin-1-yl]-(1H-indol-2-yl)-methanone

SMILES: CCOc1cccnc1N1CCN(CC1)C(=O)c1cc2ccccc2[nH]1

InChI Key: InChIKey=NWMIXFOVOGAALM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055472   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50055472 (CHEMBL356173 | [4-(3-Ethoxy-pyridin-2-yl)-piperazi...) Show SMILES CCOc1cccnc1N1CCN(CC1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C20H22N4O2/c1-2-26-18-8-5-9-21-19(18)23-10-12-24(13-11-23)20(25)17-14-15-6-3-4-7-16(15)22-17/h3-9,14,22H,2,10-13H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn Curated by ChEMBL					Assay Description In vitro for inhibition of HIV-1 reverse transcriptase.				J Med Chem 39: 5267-75 (1997) Article DOI: 10.1021/jm960269m BindingDB Entry DOI: 10.7270/Q2XK8DPT
					More data for this Ligand-Target Pair