BDBM50055478 (1H-Indol-2-yl)-[4-(3-isopropoxy-pyridin-2-yl)-piperazin-1-yl]-methanone::CHEMBL356163

SMILES: CC(C)Oc1cccnc1N1CCN(CC1)C(=O)c1cc2ccccc2[nH]1

InChI Key: InChIKey=JSKAIOMOXXDDHA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50055478 ((1H-Indol-2-yl)-[4-(3-isopropoxy-pyridin-2-yl)-pip...) Show SMILES CC(C)Oc1cccnc1N1CCN(CC1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C21H24N4O2/c1-15(2)27-19-8-5-9-22-20(19)24-10-12-25(13-11-24)21(26)18-14-16-6-3-4-7-17(16)23-18/h3-9,14-15,23H,10-13H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn Curated by ChEMBL					Assay Description In vitro for inhibition of HIV-1 reverse transcriptase.				J Med Chem 39: 5267-75 (1997) Article DOI: 10.1021/jm960269m BindingDB Entry DOI: 10.7270/Q2XK8DPT
					More data for this Ligand-Target Pair