BDBM50055627 CHEMBL268158::[(R)-1-[(R)-1-{(R)-2-Benzyloxy-1-[(R)-1-((S)-1-ethylcarbamoyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethylcarbamoyl]-ethylcarbamoyl}-2-(4-benzyloxy-phenyl)-ethylcarbamoyl]-2-(1H-imidazol-4-yl)-ethyl]-carbamic acid benzyl ester

SMILES: CCNC(=O)[C@H](C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](COCc1ccccc1)NC(=O)[C@@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1

InChI Key: InChIKey=VXQJPJFCAJWFLM-IYBRZSGVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50055627 (CHEMBL268158 | [(R)-1-[(R)-1-{(R)-2-Benzyloxy-1-[(...) Show SMILES CCNC(=O)[C@H](C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](COCc1ccccc1)NC(=O)[C@@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C56H61N9O9/c1-3-58-51(66)37(2)61-52(67)48(28-42-30-59-46-22-14-13-21-45(42)46)63-55(70)50(35-72-32-39-15-7-4-8-16-39)64-53(68)47(27-38-23-25-44(26-24-38)73-33-40-17-9-5-10-18-40)62-54(69)49(29-43-31-57-36-60-43)65-56(71)74-34-41-19-11-6-12-20-41/h4-26,30-31,36-37,47-50,59H,3,27-29,32-35H2,1-2H3,(H,57,60)(H,58,66)(H,61,67)(H,62,69)(H,63,70)(H,64,68)(H,65,71)/t37-,47+,48+,49+,50+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain farnesyltransferase				J Med Chem 40: 192-200 (1997) Article DOI: 10.1021/jm960602m BindingDB Entry DOI: 10.7270/Q2JW8FJ4
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