BDBM50055630 (S)-2-[(R)-2-{(R)-3-Benzyloxy-2-[(R)-2-[(R)-2-benzyloxycarbonylamino-3-(1H-imidazol-4-yl)-propionylamino]-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-3-(1H-indol-3-yl)-propionylamino]-propionic acid::CHEMBL413547

SMILES: C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](COCc1ccccc1)NC(=O)[C@@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)C(O)=O

InChI Key: InChIKey=TXTNVVSGAKKFIZ-ZQIGARPHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50055630 ((S)-2-[(R)-2-{(R)-3-Benzyloxy-2-[(R)-2-[(R)-2-benz...) Show SMILES C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](COCc1ccccc1)NC(=O)[C@@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C54H56N8O10/c1-35(53(67)68)58-49(63)46(26-40-28-56-44-20-12-11-19-43(40)44)60-52(66)48(33-70-30-37-13-5-2-6-14-37)61-50(64)45(25-36-21-23-42(24-22-36)71-31-38-15-7-3-8-16-38)59-51(65)47(27-41-29-55-34-57-41)62-54(69)72-32-39-17-9-4-10-18-39/h2-24,28-29,34-35,45-48,56H,25-27,30-33H2,1H3,(H,55,57)(H,58,63)(H,59,65)(H,60,66)(H,61,64)(H,62,69)(H,67,68)/t35-,45+,46+,47+,48+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain farnesyltransferase				J Med Chem 40: 192-200 (1997) Article DOI: 10.1021/jm960602m BindingDB Entry DOI: 10.7270/Q2JW8FJ4
					More data for this Ligand-Target Pair