BDBM50055645 (6E,10E,14E)-2,6,10,15,19-Pentamethyl-21-(3-methyl-oxiranyl)-henicosa-6,10,14-trien-5-one::CHEMBL67465
SMILES: CC(C)CCC(=O)C(C)C=CC\C(C)=C\CC\C=C(/C)CCCC(C)CCC1OC1C
InChI Key: InChIKey=SQWGHKOSNDTIAK-WJLDUDNZSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lanosterol synthase (Rattus norvegicus) | BDBM50055645 ((6E,10E,14E)-2,6,10,15,19-Pentamethyl-21-(3-methyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Simon Fraser University Curated by ChEMBL | Assay Description Inhibition constant against rat liver Oxidosqualene-lanosterol cyclase | J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50055645 ((6E,10E,14E)-2,6,10,15,19-Pentamethyl-21-(3-methyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Simon Fraser University Curated by ChEMBL | Assay Description Inhibition against rat liver Oxidosqualene-lanosterol cyclase | J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73 | |||||||||||
More data for this Ligand-Target Pair |