BDBM50055863 CHEMBL2252571
SMILES: O=C1C=C(NCc2ccccc2)C(=O)C=C1NCc1ccccc1
InChI Key: InChIKey=PWGGXCZVOQQDOX-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dynamin-1 (Homo sapiens (Human)) | BDBM50055863 (CHEMBL2252571) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreat... | Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR | |||||||||||
More data for this Ligand-Target Pair |