BDBM50055975 CHEMBL3325718

SMILES: CC1(C)Cc2c(c(nn2-c2ccc(Cl)cc2Cl)C(F)(F)F)C(=O)C1

InChI Key: InChIKey=LCJMHYUOSFBKDY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055975   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50055975 (CHEMBL3325718) Show SMILES CC1(C)Cc2c(c(nn2-c2ccc(Cl)cc2Cl)C(F)(F)F)C(=O)C1 Show InChI InChI=1S/C16H13Cl2F3N2O/c1-15(2)6-11-13(12(24)7-15)14(16(19,20)21)22-23(11)10-4-3-8(17)5-9(10)18/h3-5H,6-7H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...				Bioorg Med Chem 22: 4694-703 (2014) Article DOI: 10.1016/j.bmc.2014.07.012 BindingDB Entry DOI: 10.7270/Q2H133NH
					More data for this Ligand-Target Pair