null

SMILES: O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1

InChI Key: InChIKey=GFORNYWGPFXWHV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50056947   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampal membranes				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampal membranes				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Inhibition of [3H]pyrilamine binding to Histamine H1 receptor in rat cortex				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Inhibition of [3H]pyrilamine binding to Histamine H1 receptor in rat cortex				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor in rat hippocampus				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of bovine striatum				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of bovine striatum				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Inhibition of [3H]mesulergine binding to 5-hydroxytryptamine 1C receptor of pig choroid Plexus				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3B (Mus musculus)	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor in NG cells 108-15				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Sus scrofa)	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor using [3H]5-HT in pig striatum + frontalCortex				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (BOVINE)	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Inhibition of [3H]SCH-23390 binding to Dopamine receptor D1 of bovine striatum				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Inhibition of forskolin-activated adenylate cyclase (cAMP) activity at 5-hydroxytryptamine 1A receptor in rat hippocampus				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair