BDBM50057014 (10R,12R)-12-Hydroxy-6,6,10,11,11-pentamethyl-4-propyl-11,12-dihydro-6H,10H-dipyrano[2,3-f;2',3'-h]chromen-2-one::CHEMBL267679

SMILES: CCCc1cc(=O)oc2c3[C@H](O)C(C)(C)[C@@H](C)Oc3c3C=CC(C)(C)Oc3c12

InChI Key: InChIKey=CIDDLYINUXNKQS-GTJPDFRWSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50057014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50057014 ((10R,12R)-12-Hydroxy-6,6,10,11,11-pentamethyl-4-pr...) Show SMILES CCCc1cc(=O)oc2c3[C@H](O)C(C)(C)[C@@H](C)Oc3c3C=CC(C)(C)Oc3c12 |c:21| Show InChI InChI=1S/C23H28O5/c1-7-8-13-11-15(24)27-20-16(13)19-14(9-10-22(3,4)28-19)18-17(20)21(25)23(5,6)12(2)26-18/h9-12,21,25H,7-8H2,1-6H3/t12-,21+/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a
MediChem Research, Inc. Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primer				J Med Chem 40: 1005-17 (1997) Article DOI: 10.1021/jm960355m BindingDB Entry DOI: 10.7270/Q2N015NG
					More data for this Ligand-Target Pair