BDBM50057431 CHEMBL21475::[4-(4-Methoxy-phenyl)-butyl]-[2-(6-methyl-chroman-8-yloxy)-ethyl]-amine
SMILES: COc1ccc(CCCCNCCOc2cc(C)cc3CCCOc23)cc1
InChI Key: InChIKey=YEXMXGRLJXAVKY-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50057431 (CHEMBL21475 | [4-(4-Methoxy-phenyl)-butyl]-[2-(6-m...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptor | J Med Chem 40: 1252-7 (1997) Article DOI: 10.1021/jm960760d BindingDB Entry DOI: 10.7270/Q20R9Q26 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50057431 (CHEMBL21475 | [4-(4-Methoxy-phenyl)-butyl]-[2-(6-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperone | J Med Chem 40: 1252-7 (1997) Article DOI: 10.1021/jm960760d BindingDB Entry DOI: 10.7270/Q20R9Q26 | |||||||||||
More data for this Ligand-Target Pair |