BDBM50057819 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-3-(2,2-diethoxy-ethyl)-5-methyl-1H-pyrimidine-2,4-dione::CHEMBL39874

SMILES: CCOC(Cn1c(=O)c(C)cn(C2CC(N=[N+]=[N-])C(CO)O2)c1=O)OCC

InChI Key: InChIKey=JFWRWEWXIIPCDR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50057819   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50057819 (1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...) Show SMILES CCOC(Cn1c(=O)c(C)cn(C2CC(N=[N+]=[N-])C(CO)O2)c1=O)OCC Show InChI InChI=1S/C16H25N5O6/c1-4-25-14(26-5-2)8-21-15(23)10(3)7-20(16(21)24)13-6-11(18-19-17)12(9-22)27-13/h7,11-14,22H,4-6,8-9H2,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Institut de Chimie des Substances Naturelles CNRS Curated by ChEMBL					Assay Description Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.				J Med Chem 40: 1550-8 (1997) Article DOI: 10.1021/jm9600095 BindingDB Entry DOI: 10.7270/Q2TH8KSM
					More data for this Ligand-Target Pair