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BDBM50058027 CHEMBL29374

SMILES: OC(=O)CCc1cccc2CC(CCc12)NS(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=GLGCGDNKOCLHIH-UHFFFAOYNA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058027   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50058027
PNG
(CHEMBL29374)
Show SMILES OC(=O)CCc1cccc2CC(CCc12)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1/C19H20ClNO4S/c20-15-5-8-17(9-6-15)26(24,25)21-16-7-10-18-13(4-11-19(22)23)2-1-3-14(18)12-16/h1-3,5-6,8-9,16,21H,4,7,10-12H2,(H,22,23)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of human TP receptor expressed in QBI-HEK 293A cells assessed as IP3 metabolite level after 1 hr by HTRF assay


Bioorg Med Chem Lett 24: 4171-5 (2014)


Article DOI: 10.1016/j.bmcl.2014.07.047
BindingDB Entry DOI: 10.7270/Q2QF8VJ5
More data for this
Ligand-Target Pair