null

SMILES: CN1CCC23C4Oc5c2c(CC1[C@]3(O)CC1(Cc2cc3ccccc3cc2C1)C4=O)ccc5O

InChI Key: InChIKey=SCBRAASOETWQCS-HKBMUOCXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (MOUSE)	BDBM50058153 (7-(5',6'-Benzo-2'-spiroindanyl)oxymorphone | CHEMB...) Show SMILES CN1CCC23C4Oc5c2c(CC1[C@]3(O)CC1(Cc2cc3ccccc3cc2C1)C4=O)ccc5O |TLB:13:12:8.9.10:1.3.2,THB:7:8:12:1.3.2,0:1:12:8.9.10| Show InChI InChI=1S/C29H27NO4/c1-30-9-8-28-23-18-6-7-21(31)24(23)34-26(28)25(32)27(15-29(28,33)22(30)12-18)13-19-10-16-4-2-3-5-17(16)11-20(19)14-27/h2-7,10-11,22,26,31,33H,8-9,12-15H2,1H3/t22?,26?,28?,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description The compound tested for agonistic activity against [3H]- NT1 (Opioid receptor delta 1) opioid receptor				J Med Chem 40: 1720-5 (1997) Article DOI: 10.1021/jm9700880 BindingDB Entry DOI: 10.7270/Q2FB53M9
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50058153 (7-(5',6'-Benzo-2'-spiroindanyl)oxymorphone | CHEMB...) Show SMILES CN1CCC23C4Oc5c2c(CC1[C@]3(O)CC1(Cc2cc3ccccc3cc2C1)C4=O)ccc5O |TLB:13:12:8.9.10:1.3.2,THB:7:8:12:1.3.2,0:1:12:8.9.10| Show InChI InChI=1S/C29H27NO4/c1-30-9-8-28-23-18-6-7-21(31)24(23)34-26(28)25(32)27(15-29(28,33)22(30)12-18)13-19-10-16-4-2-3-5-17(16)11-20(19)14-27/h2-7,10-11,22,26,31,33H,8-9,12-15H2,1H3/t22?,26?,28?,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description The compound tested for agonistic activity against Opioid receptor mu 1 using [3H]- DAMGO as the radioligand.				J Med Chem 40: 1720-5 (1997) Article DOI: 10.1021/jm9700880 BindingDB Entry DOI: 10.7270/Q2FB53M9
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Mus musculus (Mouse))	BDBM50058153 (7-(5',6'-Benzo-2'-spiroindanyl)oxymorphone | CHEMB...) Show SMILES CN1CCC23C4Oc5c2c(CC1[C@]3(O)CC1(Cc2cc3ccccc3cc2C1)C4=O)ccc5O |TLB:13:12:8.9.10:1.3.2,THB:7:8:12:1.3.2,0:1:12:8.9.10| Show InChI InChI=1S/C29H27NO4/c1-30-9-8-28-23-18-6-7-21(31)24(23)34-26(28)25(32)27(15-29(28,33)22(30)12-18)13-19-10-16-4-2-3-5-17(16)11-20(19)14-27/h2-7,10-11,22,26,31,33H,8-9,12-15H2,1H3/t22?,26?,28?,29-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description The compound tested for agonistic activity against Opioid receptor kappa 1 using [3H]U-69,594 as the radioligand.				J Med Chem 40: 1720-5 (1997) Article DOI: 10.1021/jm9700880 BindingDB Entry DOI: 10.7270/Q2FB53M9
					More data for this Ligand-Target Pair