BDBM50058513 CHEMBL3326654
SMILES: N(c1cccnc1)c1ncnn2cccc12
InChI Key: InChIKey=KTWGHBNFKBORPM-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human)) | BDBM50058513 (CHEMBL3326654) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Binding affinity to MAP4K4 (unknown origin) by surface plasmon resonance assay | Bioorg Med Chem Lett 24: 4546-52 (2014) Article DOI: 10.1016/j.bmcl.2014.07.071 BindingDB Entry DOI: 10.7270/Q2NG4S9D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |