BDBM50058635 CHEMBL60523::N-{2-[({(1E)-[5-(4-fluorophenoxy)-2-furyl]methylene}amino)oxy]ethyl}-N-hydroxyurea

SMILES: NC(=O)N(O)CCO\N=C\c1ccc(Oc2ccc(F)cc2)o1

InChI Key: InChIKey=YVXJHGVHAYLMQS-RQZCQDPDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058635   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50058635 (CHEMBL60523 | N-{2-[({(1E)-[5-(4-fluorophenoxy)-2-...) Show SMILES NC(=O)N(O)CCO\N=C\c1ccc(Oc2ccc(F)cc2)o1 Show InChI InChI=1S/C14H14FN3O5/c15-10-1-3-11(4-2-10)22-13-6-5-12(23-13)9-17-21-8-7-18(20)14(16)19/h1-6,9,20H,7-8H2,(H2,16,19)/b17-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).				J Med Chem 40: 1955-68 (1997) Article DOI: 10.1021/jm9700474 BindingDB Entry DOI: 10.7270/Q2NV9JWT
					More data for this Ligand-Target Pair