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SMILES: O=C(N1CCC1)c1cc2c(Nc3ccncc3)ncnn2c1

InChI Key: InChIKey=SBPBMPDGYLPULR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058682   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase kinase 4


(Homo sapiens (Human))		BDBM50058682
PNG
(CHEMBL3326747)
Show SMILES O=C(N1CCC1)c1cc2c(Nc3ccncc3)ncnn2c1
Show InChI InChI=1S/C15H14N6O/c22-15(20-6-1-7-20)11-8-13-14(17-10-18-21(13)9-11)19-12-2-4-16-5-3-12/h2-5,8-10H,1,6-7H2,(H,16,17,18,19)
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n/an/a 130n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of human MAP4K4 using LGRDKYKTLRQIRQ-COOH peptide substrate by LC3K assay

Bioorg Med Chem Lett 24: 4546-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.07.071
BindingDB Entry DOI: 10.7270/Q2NG4S9D
More data for this
Ligand-Target Pair