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SMILES: COC(=O)c1ccccc1Nc1nc(Nc2ccc(CN)cc2)nc2nccn12

InChI Key: InChIKey=VIPLNRFYEITNFN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059146   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50059146
PNG
(CHEMBL3393282)
Show SMILES COC(=O)c1ccccc1Nc1nc(Nc2ccc(CN)cc2)nc2nccn12
Show InChI InChI=1S/C20H19N7O2/c1-29-17(28)15-4-2-3-5-16(15)24-20-26-18(25-19-22-10-11-27(19)20)23-14-8-6-13(12-21)7-9-14/h2-11H,12,21H2,1H3,(H2,22,23,24,25,26)
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n/an/a 240n/an/an/an/an/an/a



Universit£ Paris Descartes

Curated by ChEMBL


Assay Description
Inhibition of FAK (unknown origin) using ULight-poly GT as substrate after 1.6 hrs by TR-FRET assay

J Med Chem 58: 237-51 (2015)


Article DOI: 10.1021/jm500784e
BindingDB Entry DOI: 10.7270/Q2B27WZC
More data for this
Ligand-Target Pair