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SMILES: CNC(=O)c1ccccc1Nc1nc(Nc2ccc(cc2)C#N)n2ccnc2n1

InChI Key: InChIKey=VMKBJCZOXDBEKY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059153   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50059153
PNG
(CHEMBL3393275)
Show SMILES CNC(=O)c1ccccc1Nc1nc(Nc2ccc(cc2)C#N)n2ccnc2n1
Show InChI InChI=1S/C20H16N8O/c1-22-17(29)15-4-2-3-5-16(15)25-18-26-19-23-10-11-28(19)20(27-18)24-14-8-6-13(12-21)7-9-14/h2-11H,1H3,(H,22,29)(H2,23,24,25,26,27)
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Similars
Article
PubMed
n/an/a 1.12E+3n/an/an/an/an/an/a



Universit£ Paris Descartes

Curated by ChEMBL


Assay Description
Inhibition of FAK (unknown origin) using ULight-poly GT as substrate after 1.6 hrs by TR-FRET assay

J Med Chem 58: 237-51 (2015)


Article DOI: 10.1021/jm500784e
BindingDB Entry DOI: 10.7270/Q2B27WZC
More data for this
Ligand-Target Pair