null
SMILES: CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)C(C)(C)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O
InChI Key: InChIKey=ALLCKKBLFVTNDT-CUUBPCRASA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50059371 ((S)-3-(2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Environmental Health Sciences Curated by ChEMBL | Assay Description Affinity of the compound was assessed using competitive binding assay labeled with [3H]-DPDPE (6.3 nM) for Opioid receptor delta 1 | J Med Chem 40: 2579-87 (1997) Article DOI: 10.1021/jm9700530 BindingDB Entry DOI: 10.7270/Q25M64T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50059371 ((S)-3-(2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Environmental Health Sciences Curated by ChEMBL | Assay Description Affinity of the compound was assessed using competitive binding assay labeled with [3H]- DAGO (1.28 nM) for Opioid receptor mu 1 | J Med Chem 40: 2579-87 (1997) Article DOI: 10.1021/jm9700530 BindingDB Entry DOI: 10.7270/Q25M64T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (MOUSE) | BDBM50059371 ((S)-3-(2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 57.3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Environmental Health Sciences Curated by ChEMBL | Assay Description Functional biological activity for Opioid receptor delta 1 was determined in vitro, on mouse vas deferens (MVD). | J Med Chem 40: 2579-87 (1997) Article DOI: 10.1021/jm9700530 BindingDB Entry DOI: 10.7270/Q25M64T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50059371 ((S)-3-(2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-...) | UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Environmental Health Sciences Curated by ChEMBL | Assay Description Functional biological activity for mu opioid receptor was determined in vitro , on guinea pig ileum (GPI). | J Med Chem 40: 2579-87 (1997) Article DOI: 10.1021/jm9700530 BindingDB Entry DOI: 10.7270/Q25M64T2 | |||||||||||
More data for this Ligand-Target Pair |