BDBM50059472 2-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-octahydro-imidazo[1,5-a]pyridine::CHEMBL90384

SMILES: FC(F)(F)c1cccc(c1)N1CCN(CCCCN2CC3CCCCN3C2)CC1

InChI Key: InChIKey=FNHAUTZZAKUROD-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059472   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50059472 (2-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2CC3CCCCN3C2)CC1 Show InChI InChI=1S/C22H33F3N4/c23-22(24,25)19-6-5-8-20(16-19)28-14-12-26(13-15-28)9-3-4-10-27-17-21-7-1-2-11-29(21)18-27/h5-6,8,16,21H,1-4,7,9-15,17-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinities against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand in rat cerebral cortex membrane				J Med Chem 40: 2653-6 (1997) Article DOI: 10.1021/jm970216k BindingDB Entry DOI: 10.7270/Q2X34WKX
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50059472 (2-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2CC3CCCCN3C2)CC1 Show InChI InChI=1S/C22H33F3N4/c23-22(24,25)19-6-5-8-20(16-19)28-14-12-26(13-15-28)9-3-4-10-27-17-21-7-1-2-11-29(21)18-27/h5-6,8,16,21H,1-4,7,9-15,17-18H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinities against Alpha-1 adrenergic receptor (alpha1 adrenoceptor) using [3H]-prazosin as radioligand in rat cerebral cortex membrane				J Med Chem 40: 2653-6 (1997) Article DOI: 10.1021/jm970216k BindingDB Entry DOI: 10.7270/Q2X34WKX
					More data for this Ligand-Target Pair