BDBM50059606 2-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl)-4-phenyl-butyric acid::CHEMBL321114

SMILES: OC(=O)C(CCc1ccccc1)c1ccc2Cc3cccc(O)c3C(=O)c2c1O

InChI Key: InChIKey=UZOBICOUXZOJEI-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Bos taurus)	BDBM50059606 (2-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...) Show SMILES OC(=O)C(CCc1ccccc1)c1ccc2Cc3cccc(O)c3C(=O)c2c1O Show InChI InChI=1S/C24H20O5/c25-19-8-4-7-15-13-16-10-12-17(22(26)21(16)23(27)20(15)19)18(24(28)29)11-9-14-5-2-1-3-6-14/h1-8,10,12,18,25-26H,9,11,13H2,(H,28,29)	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Westfälische Wilhelms-Universität Münster Curated by ChEMBL					Assay Description 5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...				J Med Chem 40: 2780-7 (1997) Article DOI: 10.1021/jm9701785 BindingDB Entry DOI: 10.7270/Q28C9VB4
					More data for this Ligand-Target Pair