BDBM50059622 3-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl)-N-hydroxy-propionamide::CHEMBL94484

SMILES: ONC(=O)CCc1ccc2Cc3cccc(O)c3C(=O)c2c1O

InChI Key: InChIKey=OEOCVWYCDNVQID-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059622   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Bos taurus)	BDBM50059622 (3-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...) Show SMILES ONC(=O)CCc1ccc2Cc3cccc(O)c3C(=O)c2c1O Show InChI InChI=1S/C17H15NO5/c19-12-3-1-2-10-8-11-5-4-9(6-7-13(20)18-23)16(21)15(11)17(22)14(10)12/h1-5,19,21,23H,6-8H2,(H,18,20)	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Westfälische Wilhelms-Universität Münster Curated by ChEMBL					Assay Description 5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...				J Med Chem 40: 2780-7 (1997) Article DOI: 10.1021/jm9701785 BindingDB Entry DOI: 10.7270/Q28C9VB4
					More data for this Ligand-Target Pair