BDBM50059636 CHEMBL3218573

SMILES: CC(Nc1ccccc1)c1cc(C)cc2c1oc(cc2=O)-c1ccncc1

InChI Key: InChIKey=BWCHMAXKQWYVNL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50059636 (CHEMBL3218573) Show SMILES CC(Nc1ccccc1)c1cc(C)cc2c1oc(cc2=O)-c1ccncc1 Show InChI InChI=1S/C23H20N2O2/c1-15-12-19(16(2)25-18-6-4-3-5-7-18)23-20(13-15)21(26)14-22(27-23)17-8-10-24-11-9-17/h3-14,16,25H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital Hradec Kralove Curated by ChEMBL					Assay Description Inhibition of PI3K p110beta (unknown origin)				J Med Chem 58: 41-71 (2015) Article DOI: 10.1021/jm501026z BindingDB Entry DOI: 10.7270/Q2P84DJ7
					More data for this Ligand-Target Pair