null
SMILES: Cn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O
InChI Key: InChIKey=YXLQKZHKWIKJKC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50059672 ((S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 330 | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description In vitro activity of the compound at Ionotropic glutamate receptor using cortical wedge assays in rat brain synaptosoma | J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50059672 ((S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA1 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50059672 ((S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA4 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM50059672 ((S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA3 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50059672 ((S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA2(R) expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair |