BDBM50059678 7-[(5-Carbamimidoyl-3-methyl-1H-indole-2-carbonyl)-amino]-heptanoic acid::CHEMBL97675
SMILES: Cc1c([nH]c2ccc(cc12)C(N)=N)C(=O)NCCCCCCC(O)=O
InChI Key: InChIKey=UMFSBVXISUTTIH-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50059678 (7-[(5-Carbamimidoyl-3-methyl-1H-indole-2-carbonyl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Antagonism of fibrinogen binding to a purified human fibrinogen receptor preparation. | J Med Chem 40: 2843-57 (1997) Article DOI: 10.1021/jm970020k BindingDB Entry DOI: 10.7270/Q24M93MS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50059678 (7-[(5-Carbamimidoyl-3-methyl-1H-indole-2-carbonyl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of the platelet GPIIb-IIIa receptor measured as ability to attenuate ADP-induced (fibrinogen-mediated) platelet aggregation in human plate... | J Med Chem 40: 2843-57 (1997) Article DOI: 10.1021/jm970020k BindingDB Entry DOI: 10.7270/Q24M93MS | |||||||||||
More data for this Ligand-Target Pair |