BDBM50059749 3-Methyl-4-phenyl-quinoline-2-carboxylic acid benzyl-methyl-amide::CHEMBL15248

SMILES: CN(Cc1ccccc1)C(=O)c1nc2ccccc2c(c1C)-c1ccccc1

InChI Key: InChIKey=LMAZVQQMVXMTEY-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50059749   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat))	BDBM50059749 (3-Methyl-4-phenyl-quinoline-2-carboxylic acid benz...) Show SMILES CN(Cc1ccccc1)C(=O)c1nc2ccccc2c(c1C)-c1ccccc1 Show InChI InChI=1S/C25H22N2O/c1-18-23(20-13-7-4-8-14-20)21-15-9-10-16-22(21)26-24(18)25(28)27(2)17-19-11-5-3-6-12-19/h3-16H,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description In vitro binding affinity (pIC50) was tested against peripheral benzodiazepine receptor (PBR) in rat.				J Med Chem 40: 2910-21 (1997) Article DOI: 10.1021/jm960516m BindingDB Entry DOI: 10.7270/Q2KW5GQZ
					More data for this Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat))	BDBM50059749 (3-Methyl-4-phenyl-quinoline-2-carboxylic acid benz...) Show SMILES CN(Cc1ccccc1)C(=O)c1nc2ccccc2c(c1C)-c1ccccc1 Show InChI InChI=1S/C25H22N2O/c1-18-23(20-13-7-4-8-14-20)21-15-9-10-16-22(21)26-24(18)25(28)27(2)17-19-11-5-3-6-12-19/h3-16H,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat))	BDBM50059749 (3-Methyl-4-phenyl-quinoline-2-carboxylic acid benz...) Show SMILES CN(Cc1ccccc1)C(=O)c1nc2ccccc2c(c1C)-c1ccccc1 Show InChI InChI=1S/C25H22N2O/c1-18-23(20-13-7-4-8-14-20)21-15-9-10-16-22(21)26-24(18)25(28)27(2)17-19-11-5-3-6-12-19/h3-16H,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Magna Graecia di Catanzaro Curated by ChEMBL					Assay Description Test in vitro, for potential ability to displace [3H]1 from PBR in rat brain cortex				J Med Chem 44: 1134-50 (2001) BindingDB Entry DOI: 10.7270/Q2G161KM
					More data for this Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat))	BDBM50059749 (3-Methyl-4-phenyl-quinoline-2-carboxylic acid benz...) Show SMILES CN(Cc1ccccc1)C(=O)c1nc2ccccc2c(c1C)-c1ccccc1 Show InChI InChI=1S/C25H22N2O/c1-18-23(20-13-7-4-8-14-20)21-15-9-10-16-22(21)26-24(18)25(28)27(2)17-19-11-5-3-6-12-19/h3-16H,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description In vitro displacement of [3H]PK11195 from the peripheral benzodiazepine receptor (PBR) in rat cortex				J Med Chem 40: 2910-21 (1997) Article DOI: 10.1021/jm960516m BindingDB Entry DOI: 10.7270/Q2KW5GQZ
					More data for this Ligand-Target Pair