BDBM50059844 CHEMBL319271::[(R)-1-[(S)-1-(2-Benzyloxy-ethylcarbamoyl)-2-(4-benzyloxy-phenyl)-ethylcarbamoyl]-2-(1H-imidazol-4-yl)-ethyl]-carbamic acid benzyl ester

SMILES: O=C(N[C@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NCCOCc1ccccc1)OCc1ccccc1

InChI Key: InChIKey=WSTHABWJAPYXLV-MPQUPPDSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50059844 (CHEMBL319271 | [(R)-1-[(S)-1-(2-Benzyloxy-ethylcar...) Show SMILES O=C(N[C@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NCCOCc1ccccc1)OCc1ccccc1 Show InChI InChI=1S/C39H41N5O6/c45-37(41-20-21-48-25-30-10-4-1-5-11-30)35(22-29-16-18-34(19-17-29)49-26-31-12-6-2-7-13-31)43-38(46)36(23-33-24-40-28-42-33)44-39(47)50-27-32-14-8-3-9-15-32/h1-19,24,28,35-36H,20-23,25-27H2,(H,40,42)(H,41,45)(H,43,46)(H,44,47)/t35-,36+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Activity against Farnesyltransferase				J Med Chem 40: 2971-90 (1997) Article DOI: 10.1021/jm970226l BindingDB Entry DOI: 10.7270/Q26M37HF
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