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SMILES: COC(=O)C(CCSC)NC(=O)CN1c2ccccc2C(N[C@@H](N(C)C(=O)[C@H](N)CS)C1=O)c1ccccc1

InChI Key: InChIKey=UCPBEFVDPWTBKC-VAUYKUKKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059861   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50059861
PNG
(2-(2-{(S)-3-[((S)-2-Amino-3-mercapto-propionyl)-me...)
Show SMILES COC(=O)C(CCSC)NC(=O)CN1c2ccccc2C(N[C@@H](N(C)C(=O)[C@H](N)CS)C1=O)c1ccccc1
Show InChI InChI=1S/C27H35N5O5S2/c1-31(25(34)19(28)16-38)24-26(35)32(15-22(33)29-20(13-14-39-3)27(36)37-2)21-12-8-7-11-18(21)23(30-24)17-9-5-4-6-10-17/h4-12,19-20,23-24,30,38H,13-16,28H2,1-3H3,(H,29,33)/t19-,20?,23?,24+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.850n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Activity against rat Farnesyltransferase

J Med Chem 40: 2971-90 (1997)


Article DOI: 10.1021/jm970226l
BindingDB Entry DOI: 10.7270/Q26M37HF
More data for this
Ligand-Target Pair