BDBM50060058 CHEMBL3394354

SMILES: CC(C)Cc1ccc(cn1)-c1c(C)nc2c(nccn12)N1CCOCC1

InChI Key: InChIKey=ZATRGTBLBNRSEM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50060058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM50060058 (CHEMBL3394354) Show SMILES CC(C)Cc1ccc(cn1)-c1c(C)nc2c(nccn12)N1CCOCC1 Show InChI InChI=1S/C20H25N5O/c1-14(2)12-17-5-4-16(13-22-17)18-15(3)23-20-19(21-6-7-25(18)20)24-8-10-26-11-9-24/h4-7,13-14H,8-12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	182	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of rat recombinant PDE10A expressed in Sf9 cells using [3H]cAMP substrate incubated for 60 mins by topcount scintillation counting method				J Med Chem 58: 978-93 (2015) Article DOI: 10.1021/jm501651a BindingDB Entry DOI: 10.7270/Q2CV4KDK
					More data for this Ligand-Target Pair