BDBM50060139 CHEMBL326352::[(S)-1-((4-Benzyloxy-benzyl)-{[(1-phenyl-cyclobutylmethyl)-carbamoyl]-methyl}-carbamoyl)-2-(3H-imidazol-4-yl)-ethyl]-carbamic acid benzyl ester

SMILES: O=C(CN(Cc1ccc(OCc2ccccc2)cc1)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)NCC1(CCC1)c1ccccc1

InChI Key: InChIKey=HNXRTWHXWCHGID-QNGWXLTQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50060139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50060139 (CHEMBL326352 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...) Show SMILES O=C(CN(Cc1ccc(OCc2ccccc2)cc1)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)NCC1(CCC1)c1ccccc1 Show InChI InChI=1S/C41H43N5O5/c47-38(43-29-41(21-10-22-41)34-15-8-3-9-16-34)26-46(25-31-17-19-36(20-18-31)50-27-32-11-4-1-5-12-32)39(48)37(23-35-24-42-30-44-35)45-40(49)51-28-33-13-6-2-7-14-33/h1-9,11-20,24,30,37H,10,21-23,25-29H2,(H,42,44)(H,43,47)(H,45,49)/t37-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro inhibition of rat farnesyltransferase.				J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50060139 (CHEMBL326352 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...) Show SMILES O=C(CN(Cc1ccc(OCc2ccccc2)cc1)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)NCC1(CCC1)c1ccccc1 Show InChI InChI=1S/C41H43N5O5/c47-38(43-29-41(21-10-22-41)34-15-8-3-9-16-34)26-46(25-31-17-19-36(20-18-31)50-27-32-11-4-1-5-12-32)39(48)37(23-35-24-42-30-44-35)45-40(49)51-28-33-13-6-2-7-14-33/h1-9,11-20,24,30,37H,10,21-23,25-29H2,(H,42,44)(H,43,47)(H,45,49)/t37-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .				J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG
					More data for this Ligand-Target Pair