BDBM50060264 4-Methyl-5-(2-oxo-3-m-tolyl-imidazolidin-1-ylmethyl)-3H-imidazol-1-ium
SMILES: Cc1[nH]c[nH+]c1CN1CCN(C1=O)c1cccc(C)c1
InChI Key: InChIKey=WJZWQSHGJKMWIS-UHFFFAOYSA-O
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM50060264 (4-Methyl-5-(2-oxo-3-m-tolyl-imidazolidin-1-ylmethy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.930 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia& Upjohn Curated by ChEMBL | Assay Description In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]BRL-43694 from rat entorhinal cortex | J Med Chem 40: 3369-80 (1997) Article DOI: 10.1021/jm970060o BindingDB Entry DOI: 10.7270/Q2X63NNK | |||||||||||
More data for this Ligand-Target Pair |