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BDBM50060271 1-(1-Aza-bicyclo[2.2.2]oct-3-yl)-3-phenyl-imidazolidin-2-one::CHEMBL114387

SMILES: O=C1N(CCN1c1ccccc1)C1CN2CCC1CC2

InChI Key: InChIKey=FBCZFWFTGPFXAA-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50060271   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)		BDBM50060271
PNG
(1-(1-Aza-bicyclo[2.2.2]oct-3-yl)-3-phenyl-imidazol...)
Show SMILES O=C1N(CCN1c1ccccc1)C1CN2CCC1CC2 |THB:2:12:16.15:18.19,(4.37,-12.53,;5.53,-13.56,;7.04,-13.22,;7.81,-14.57,;6.78,-15.71,;5.38,-15.08,;4.05,-15.88,;4.05,-17.43,;2.71,-18.2,;1.38,-17.43,;1.38,-15.88,;2.71,-15.1,;7.65,-11.8,;7.87,-10.39,;9.14,-9.01,;8.69,-8.01,;8.27,-9.11,;8.82,-10.36,;10.65,-10.6,;10.94,-9.23,)|
Show InChI InChI=1S/C16H21N3O/c20-16-18(14-4-2-1-3-5-14)10-11-19(16)15-12-17-8-6-13(15)7-9-17/h1-5,13,15H,6-12H2
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Article
PubMed
 8n/an/an/an/an/an/an/an/a



Pharmacia& Upjohn

Curated by ChEMBL


Assay Description
In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]BRL-43694 from rat entorhinal cortex

J Med Chem 40: 3369-80 (1997)


Article DOI: 10.1021/jm970060o
BindingDB Entry DOI: 10.7270/Q2X63NNK
More data for this
Ligand-Target Pair