BindingDB logo
myBDB logout

BDBM50060273 1-(1-Aza-bicyclo[2.2.2]oct-3-yl)-3-m-tolyl-imidazolidin-2-one::CHEMBL114093

SMILES: Cc1cccc(c1)N1CCN(C2CN3CCC2CC3)C1=O

InChI Key: InChIKey=OFCTVKSXYLTEMI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50060273   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)		BDBM50060273
PNG
(1-(1-Aza-bicyclo[2.2.2]oct-3-yl)-3-m-tolyl-imidazo...)
Show SMILES Cc1cccc(c1)N1CCN(C2CN3CCC2CC3)C1=O |THB:10:11:15.14:17.18,(3.63,-19.42,;4.95,-20.19,;4.95,-21.73,;6.27,-22.5,;7.61,-21.73,;7.61,-20.19,;6.27,-19.42,;8.95,-19.41,;10.34,-20.03,;11.37,-18.88,;10.6,-17.55,;11.23,-16.14,;11.43,-14.71,;12.71,-13.33,;12.27,-12.33,;11.84,-13.42,;12.38,-14.67,;14.21,-14.93,;14.5,-13.55,;9.09,-17.88,;7.94,-16.85,)|
Show InChI InChI=1S/C17H23N3O/c1-13-3-2-4-15(11-13)19-9-10-20(17(19)21)16-12-18-7-5-14(16)6-8-18/h2-4,11,14,16H,5-10,12H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 4n/an/an/an/an/an/an/an/a



Pharmacia& Upjohn

Curated by ChEMBL


Assay Description
In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]BRL-43694 from rat entorhinal cortex

J Med Chem 40: 3369-80 (1997)


Article DOI: 10.1021/jm970060o
BindingDB Entry DOI: 10.7270/Q2X63NNK
More data for this
Ligand-Target Pair