BindingDB logo
myBDB logout

BDBM50060274 1-(1-Aza-bicyclo[2.2.2]oct-3-yl)-3-(3-bromo-phenyl)-imidazolidin-2-one::CHEMBL333144

SMILES: Brc1cccc(c1)N1CCN(C2CN3CCC2CC3)C1=O

InChI Key: InChIKey=VZMCDKPXCHQQLB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50060274   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)		BDBM50060274
PNG
(1-(1-Aza-bicyclo[2.2.2]oct-3-yl)-3-(3-bromo-phenyl...)
Show SMILES Brc1cccc(c1)N1CCN(C2CN3CCC2CC3)C1=O |TLB:10:11:15.14:17.18,(7,-9.48,;8.35,-10.25,;8.35,-11.79,;9.67,-12.56,;11.02,-11.79,;11.02,-10.25,;9.67,-9.48,;12.33,-9.44,;13.74,-10.08,;14.77,-8.93,;14,-7.58,;14.61,-6.17,;14.83,-4.76,;16.08,-3.38,;17.88,-3.6,;17.59,-4.98,;15.76,-4.73,;15.22,-3.48,;15.64,-2.38,;12.49,-7.94,;11.34,-6.91,)|
Show InChI InChI=1S/C16H20BrN3O/c17-13-2-1-3-14(10-13)19-8-9-20(16(19)21)15-11-18-6-4-12(15)5-7-18/h1-3,10,12,15H,4-9,11H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 3n/an/an/an/an/an/an/an/a



Pharmacia& Upjohn

Curated by ChEMBL


Assay Description
In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]BRL-43694 from rat entorhinal cortex

J Med Chem 40: 3369-80 (1997)


Article DOI: 10.1021/jm970060o
BindingDB Entry DOI: 10.7270/Q2X63NNK
More data for this
Ligand-Target Pair