BDBM50060480 9-Amino-2,3-dimethyl-2,3-dihydro-1H-cyclopenta[b]quinolin-3-ol::CHEMBL115580

SMILES: CC1Cc2c(nc3ccccc3c2N)C1(C)O

InChI Key: InChIKey=LEKKTQIRJGFRFP-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060480   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50060480 (9-Amino-2,3-dimethyl-2,3-dihydro-1H-cyclopenta[b]q...) Show SMILES CC1Cc2c(nc3ccccc3c2N)C1(C)O Show InChI InChI=1S/C14H16N2O/c1-8-7-10-12(15)9-5-3-4-6-11(9)16-13(10)14(8,2)17/h3-6,8,17H,7H2,1-2H3,(H2,15,16)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of neuronal uptake of 5 - Hydroxytryptamine in rat brain homogenate				J Med Chem 40: 3516-23 (1997) Article DOI: 10.1021/jm970150t BindingDB Entry DOI: 10.7270/Q25H7FC9
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50060480 (9-Amino-2,3-dimethyl-2,3-dihydro-1H-cyclopenta[b]q...) Show SMILES CC1Cc2c(nc3ccccc3c2N)C1(C)O Show InChI InChI=1S/C14H16N2O/c1-8-7-10-12(15)9-5-3-4-6-11(9)16-13(10)14(8,2)17/h3-6,8,17H,7H2,1-2H3,(H2,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of AChE				Eur J Med Chem 45: 1167-72 (2010) Article DOI: 10.1016/j.ejmech.2009.12.038 BindingDB Entry DOI: 10.7270/Q25H7GFM
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50060480 (9-Amino-2,3-dimethyl-2,3-dihydro-1H-cyclopenta[b]q...) Show SMILES CC1Cc2c(nc3ccccc3c2N)C1(C)O Show InChI InChI=1S/C14H16N2O/c1-8-7-10-12(15)9-5-3-4-6-11(9)16-13(10)14(8,2)17/h3-6,8,17H,7H2,1-2H3,(H2,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description In vitro inhibition of acetylcholinesterase, isolated from rat brain.				J Med Chem 40: 3516-23 (1997) Article DOI: 10.1021/jm970150t BindingDB Entry DOI: 10.7270/Q25H7FC9
					More data for this Ligand-Target Pair
Cholinesterases (Homo sapiens (Human))	BDBM50060480 (9-Amino-2,3-dimethyl-2,3-dihydro-1H-cyclopenta[b]q...) Show SMILES CC1Cc2c(nc3ccccc3c2N)C1(C)O Show InChI InChI=1S/C14H16N2O/c1-8-7-10-12(15)9-5-3-4-6-11(9)16-13(10)14(8,2)17/h3-6,8,17H,7H2,1-2H3,(H2,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description In vitro inhibition of Butyrylcholinesterase from human plasma.				J Med Chem 40: 3516-23 (1997) Article DOI: 10.1021/jm970150t BindingDB Entry DOI: 10.7270/Q25H7FC9
					More data for this Ligand-Target Pair