BDBM50060482 1,15,15-trimethyl-3-azatetracyclo[10.2.1.0^{2,11}.0^{4,9}]pentadeca-2(11),3,5,7,9-pentaen-10-amine::9-Amino-1,4-methano-1,2,3,4-tetrahydro-4,11,11-trimethylacridine::CHEMBL331637

SMILES: CC1(C)C2CCC1(C)c1nc3ccccc3c(N)c21

InChI Key: InChIKey=KPUIFTXPWPFNOS-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060482   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50060482 (1,15,15-trimethyl-3-azatetracyclo[10.2.1.0^{2,11}....) Show SMILES CC1(C)C2CCC1(C)c1nc3ccccc3c(N)c21 Show InChI InChI=1S/C17H20N2/c1-16(2)11-8-9-17(16,3)15-13(11)14(18)10-6-4-5-7-12(10)19-15/h4-7,11H,8-9H2,1-3H3,(H2,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description In vitro inhibition of acetylcholinesterase, isolated from rat brain.				J Med Chem 40: 3516-23 (1997) Article DOI: 10.1021/jm970150t BindingDB Entry DOI: 10.7270/Q25H7FC9
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50060482 (1,15,15-trimethyl-3-azatetracyclo[10.2.1.0^{2,11}....) Show SMILES CC1(C)C2CCC1(C)c1nc3ccccc3c(N)c21 Show InChI InChI=1S/C17H20N2/c1-16(2)11-8-9-17(16,3)15-13(11)14(18)10-6-4-5-7-12(10)19-15/h4-7,11H,8-9H2,1-3H3,(H2,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of AChE				Eur J Med Chem 45: 1167-72 (2010) Article DOI: 10.1016/j.ejmech.2009.12.038 BindingDB Entry DOI: 10.7270/Q25H7GFM
					More data for this Ligand-Target Pair
Cholinesterases (Homo sapiens (Human))	BDBM50060482 (1,15,15-trimethyl-3-azatetracyclo[10.2.1.0^{2,11}....) Show SMILES CC1(C)C2CCC1(C)c1nc3ccccc3c(N)c21 Show InChI InChI=1S/C17H20N2/c1-16(2)11-8-9-17(16,3)15-13(11)14(18)10-6-4-5-7-12(10)19-15/h4-7,11H,8-9H2,1-3H3,(H2,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description In vitro inhibition of Butyrylcholinesterase from human plasma.				J Med Chem 40: 3516-23 (1997) Article DOI: 10.1021/jm970150t BindingDB Entry DOI: 10.7270/Q25H7FC9
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50060482 (1,15,15-trimethyl-3-azatetracyclo[10.2.1.0^{2,11}....) Show SMILES CC1(C)C2CCC1(C)c1nc3ccccc3c(N)c21 Show InChI InChI=1S/C17H20N2/c1-16(2)11-8-9-17(16,3)15-13(11)14(18)10-6-4-5-7-12(10)19-15/h4-7,11H,8-9H2,1-3H3,(H2,18,19)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of neuronal uptake of 5 - Hydroxytryptamine in rat brain homogenate				J Med Chem 40: 3516-23 (1997) Article DOI: 10.1021/jm970150t BindingDB Entry DOI: 10.7270/Q25H7FC9
					More data for this Ligand-Target Pair