BDBM50060634 (S)-2-Amino-3-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-propionic acid::CHEMBL122656

SMILES: N[C@@H](Cn1ncc(=O)[nH]c1=O)C(O)=O

InChI Key: InChIKey=YUUMCVSQULVXBC-VKHMYHEASA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRIA1 (Homo sapiens (Human))	BDBM50060634 ((S)-2-Amino-3-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]tri...) Show SMILES N[C@@H](Cn1ncc(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C6H8N4O4/c7-3(5(12)13)2-10-6(14)9-4(11)1-8-10/h1,3H,2,7H2,(H,12,13)(H,9,11,14)/t3-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	163	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 1 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic AMPA (Homo sapiens (Human))	BDBM50060634 ((S)-2-Amino-3-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]tri...) Show SMILES N[C@@H](Cn1ncc(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C6H8N4O4/c7-3(5(12)13)2-10-6(14)9-4(11)1-8-10/h1,3H,2,7H2,(H,12,13)(H,9,11,14)/t3-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	189	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 4 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
					More data for this Ligand-Target Pair
GRIA2 (Homo sapiens (Human))	BDBM50060634 ((S)-2-Amino-3-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]tri...) Show SMILES N[C@@H](Cn1ncc(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C6H8N4O4/c7-3(5(12)13)2-10-6(14)9-4(11)1-8-10/h1,3H,2,7H2,(H,12,13)(H,9,11,14)/t3-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	461	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
					More data for this Ligand-Target Pair
Grik5 (Homo sapiens (Human))	BDBM50060634 ((S)-2-Amino-3-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]tri...) Show SMILES N[C@@H](Cn1ncc(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C6H8N4O4/c7-3(5(12)13)2-10-6(14)9-4(11)1-8-10/h1,3H,2,7H2,(H,12,13)(H,9,11,14)/t3-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]kainate from human Ionotropic glutamate receptor ionotropic kainate 1 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
					More data for this Ligand-Target Pair