null

SMILES: COc1ccc(CCOC[C@H](O)CN2CN(c3ccc(F)cc3)C3(CCN(CC4CCCCCCC4)CC3)C2=O)cc1OC

InChI Key: InChIKey=MQYSDUGGEGGHKZ-WJOKGBTCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50060902   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50060902 (CHEMBL3394755) Show SMILES COc1ccc(CCOC[C@H](O)CN2CN(c3ccc(F)cc3)C3(CCN(CC4CCCCCCC4)CC3)C2=O)cc1OC |r| Show InChI InChI=1S/C35H50FN3O5/c1-42-32-15-10-27(22-33(32)43-2)16-21-44-25-31(40)24-38-26-39(30-13-11-29(36)12-14-30)35(34(38)41)17-19-37(20-18-35)23-28-8-6-4-3-5-7-9-28/h10-15,22,28,31,40H,3-9,16-21,23-26H2,1-2H3/t31-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
West Chester University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human Mu opioid receptor expressed in HEK293 cells after 2 hrs by scintillation counting				Bioorg Med Chem Lett 25: 602-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.015 BindingDB Entry DOI: 10.7270/Q23B61S0
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50060902 (CHEMBL3394755) Show SMILES COc1ccc(CCOC[C@H](O)CN2CN(c3ccc(F)cc3)C3(CCN(CC4CCCCCCC4)CC3)C2=O)cc1OC |r| Show InChI InChI=1S/C35H50FN3O5/c1-42-32-15-10-27(22-33(32)43-2)16-21-44-25-31(40)24-38-26-39(30-13-11-29(36)12-14-30)35(34(38)41)17-19-37(20-18-35)23-28-8-6-4-3-5-7-9-28/h10-15,22,28,31,40H,3-9,16-21,23-26H2,1-2H3/t31-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
West Chester University Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation counting				Bioorg Med Chem Lett 25: 602-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.015 BindingDB Entry DOI: 10.7270/Q23B61S0
					More data for this Ligand-Target Pair