BDBM50061326 CHEMBL131484::[2-(4-Chloro-phenoxy)-ethyl]-(3-p-tolyloxy-propyl)-amine

SMILES: Cc1ccc(OCCCNCCOc2ccc(Cl)cc2)cc1

InChI Key: InChIKey=TXYPYDVBBSFEGP-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50061326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50061326 (CHEMBL131484 | [2-(4-Chloro-phenoxy)-ethyl]-(3-p-t...) Show SMILES Cc1ccc(OCCCNCCOc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C18H22ClNO2/c1-15-3-7-17(8-4-15)21-13-2-11-20-12-14-22-18-9-5-16(19)6-10-18/h3-10,20H,2,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human dopamine receptor D4 expressed in CHO cells by displacement of [3H]-spiperone				J Med Chem 40: 4026-9 (1998) Article DOI: 10.1021/jm970422s BindingDB Entry DOI: 10.7270/Q22J69Z9
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50061326 (CHEMBL131484 | [2-(4-Chloro-phenoxy)-ethyl]-(3-p-t...) Show SMILES Cc1ccc(OCCCNCCOc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C18H22ClNO2/c1-15-3-7-17(8-4-15)21-13-2-11-20-12-14-22-18-9-5-16(19)6-10-18/h3-10,20H,2,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Binding affinity to displace [3H]spiperone from cloned human dopamine receptor D4 was determined				Bioorg Med Chem Lett 15: 2149-57 (2005) Article DOI: 10.1016/j.bmcl.2005.02.012 BindingDB Entry DOI: 10.7270/Q2RR20G2
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50061326 (CHEMBL131484 | [2-(4-Chloro-phenoxy)-ethyl]-(3-p-t...) Show SMILES Cc1ccc(OCCCNCCOc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C18H22ClNO2/c1-15-3-7-17(8-4-15)21-13-2-11-20-12-14-22-18-9-5-16(19)6-10-18/h3-10,20H,2,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity against cloned human dopamine receptor D3 expressed in Chinese hamster ovary (CHO) K-1 cells by displacement of [3H]-spiperone.				J Med Chem 40: 4026-9 (1998) Article DOI: 10.1021/jm970422s BindingDB Entry DOI: 10.7270/Q22J69Z9
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50061326 (CHEMBL131484 | [2-(4-Chloro-phenoxy)-ethyl]-(3-p-t...) Show SMILES Cc1ccc(OCCCNCCOc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C18H22ClNO2/c1-15-3-7-17(8-4-15)21-13-2-11-20-12-14-22-18-9-5-16(19)6-10-18/h3-10,20H,2,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	178	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Binding affinity to displace [3H]spiperone from cloned human dopamine receptor D3 was determined				Bioorg Med Chem Lett 15: 2149-57 (2005) Article DOI: 10.1016/j.bmcl.2005.02.012 BindingDB Entry DOI: 10.7270/Q2RR20G2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50061326 (CHEMBL131484 | [2-(4-Chloro-phenoxy)-ethyl]-(3-p-t...) Show SMILES Cc1ccc(OCCCNCCOc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C18H22ClNO2/c1-15-3-7-17(8-4-15)21-13-2-11-20-12-14-22-18-9-5-16(19)6-10-18/h3-10,20H,2,11-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Binding affinity to displace [3H]spiperone from cloned human dopamine receptor D2 was determined				Bioorg Med Chem Lett 15: 2149-57 (2005) Article DOI: 10.1016/j.bmcl.2005.02.012 BindingDB Entry DOI: 10.7270/Q2RR20G2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50061326 (CHEMBL131484 | [2-(4-Chloro-phenoxy)-ethyl]-(3-p-t...) Show SMILES Cc1ccc(OCCCNCCOc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C18H22ClNO2/c1-15-3-7-17(8-4-15)21-13-2-11-20-12-14-22-18-9-5-16(19)6-10-18/h3-10,20H,2,11-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity against cloned human dopamine receptor D2 expressed in Chinese hamster ovary (CHO) K-1 cells by displacement of [3H]-spiperone.				J Med Chem 40: 4026-9 (1998) Article DOI: 10.1021/jm970422s BindingDB Entry DOI: 10.7270/Q22J69Z9
					More data for this Ligand-Target Pair