BDBM50061355 CHEMBL3393832

SMILES: CC1CCN(CC1)c1nc(ccc1CNC(=O)Nc1ccc2cnncc2c1)C(F)(F)F

InChI Key: InChIKey=PBGUWLXRCIKEHP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50061355 (CHEMBL3393832) Show SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Nc1ccc2cnncc2c1)C(F)(F)F Show InChI InChI=1S/C22H23F3N6O/c1-14-6-8-31(9-7-14)20-16(3-5-19(30-20)22(23,24)25)11-26-21(32)29-18-4-2-15-12-27-28-13-17(15)10-18/h2-5,10,12-14H,6-9,11H2,1H3,(H2,26,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced effect by FLIPR assay				Bioorg Med Chem Lett 25: 803-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.086 BindingDB Entry DOI: 10.7270/Q2JD4ZG3
					More data for this Ligand-Target Pair