BDBM50061573 CHEMBL3393882

SMILES: Fc1ccccc1C(=O)Nc1nc2ccccc2n1CCN1CCCC1

InChI Key: InChIKey=ONKPVKZKHPVZII-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50061573 (CHEMBL3393882) Show SMILES Fc1ccccc1C(=O)Nc1nc2ccccc2n1CCN1CCCC1 Show InChI InChI=1S/C20H21FN4O/c21-16-8-2-1-7-15(16)19(26)23-20-22-17-9-3-4-10-18(17)25(20)14-13-24-11-5-6-12-24/h1-4,7-10H,5-6,11-14H2,(H,22,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	423	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Agonist activity at human kappa opioid receptor expressed in COS7 cells after 60 mins IP1 assay				Bioorg Med Chem Lett 25: 887-92 (2015) Article DOI: 10.1016/j.bmcl.2014.12.064 BindingDB Entry DOI: 10.7270/Q2542Q8K
					More data for this Ligand-Target Pair