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Enter Data

null

SMILES: CC1(C)CCC(C)(C)c2cc3c(Sc4ccccc4N=C3c3ccc(cc3)C(O)=O)cc12

InChI Key: InChIKey=PFGCWQPTOKPRRK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50061618
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Retinoic acid receptor beta (Homo sapiens (Human))	BDBM50061618 (4-(7,7,10,10-Tetramethyl-7,8,9,10-tetrahydro-5-thi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Synergistic activity of the compound towards retinoic acid receptor-beta				J Med Chem 40: 4222-34 (1998) Article DOI: 10.1021/jm9704309 BindingDB Entry DOI: 10.7270/Q21J98VC
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Homo sapiens (Human))	BDBM50061618 (4-(7,7,10,10-Tetramethyl-7,8,9,10-tetrahydro-5-thi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Synergistic activity of the compound towards retinoid X receptor-beta				J Med Chem 40: 4222-34 (1998) Article DOI: 10.1021/jm9704309 BindingDB Entry DOI: 10.7270/Q21J98VC
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Homo sapiens (Human))	BDBM50061618 (4-(7,7,10,10-Tetramethyl-7,8,9,10-tetrahydro-5-thi...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Synergistic activity of the compound towards retinoid X receptor-gamma				J Med Chem 40: 4222-34 (1998) Article DOI: 10.1021/jm9704309 BindingDB Entry DOI: 10.7270/Q21J98VC
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50061618 (4-(7,7,10,10-Tetramethyl-7,8,9,10-tetrahydro-5-thi...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Synergistic activity of the compound towards retinoid X receptor-alpha				J Med Chem 40: 4222-34 (1998) Article DOI: 10.1021/jm9704309 BindingDB Entry DOI: 10.7270/Q21J98VC
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50061618 (4-(7,7,10,10-Tetramethyl-7,8,9,10-tetrahydro-5-thi...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Synergistic activity of the compound towards retinoic acid receptor-alpha				J Med Chem 40: 4222-34 (1998) Article DOI: 10.1021/jm9704309 BindingDB Entry DOI: 10.7270/Q21J98VC
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair