BDBM50061673 2-{[3-(Quinolin-7-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL135183

SMILES: Oc1ccc2CCC(CNCCCOc3ccc4cccnc4c3)Oc2c1

InChI Key: InChIKey=CPMKULWZFNXOBS-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061673   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50061673 (2-{[3-(Quinolin-7-yloxy)-propylamino]-methyl}-chro...) Show SMILES Oc1ccc2CCC(CNCCCOc3ccc4cccnc4c3)Oc2c1 Show InChI InChI=1S/C22H24N2O3/c25-18-7-4-17-6-9-20(27-22(17)13-18)15-23-10-2-12-26-19-8-5-16-3-1-11-24-21(16)14-19/h1,3-5,7-8,11,13-14,20,23,25H,2,6,9-10,12,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...				J Med Chem 40: 4235-56 (1998) Article DOI: 10.1021/jm9703653 BindingDB Entry DOI: 10.7270/Q2KP82TD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50061673 (2-{[3-(Quinolin-7-yloxy)-propylamino]-methyl}-chro...) Show SMILES Oc1ccc2CCC(CNCCCOc3ccc4cccnc4c3)Oc2c1 Show InChI InChI=1S/C22H24N2O3/c25-18-7-4-17-6-9-20(27-22(17)13-18)15-23-10-2-12-26-19-8-5-16-3-1-11-24-21(16)14-19/h1,3-5,7-8,11,13-14,20,23,25H,2,6,9-10,12,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity to rat hippocampal 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand				J Med Chem 40: 4235-56 (1998) Article DOI: 10.1021/jm9703653 BindingDB Entry DOI: 10.7270/Q2KP82TD
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50061673 (2-{[3-(Quinolin-7-yloxy)-propylamino]-methyl}-chro...) Show SMILES Oc1ccc2CCC(CNCCCOc3ccc4cccnc4c3)Oc2c1 Show InChI InChI=1S/C22H24N2O3/c25-18-7-4-17-6-9-20(27-22(17)13-18)15-23-10-2-12-26-19-8-5-16-3-1-11-24-21(16)14-19/h1,3-5,7-8,11,13-14,20,23,25H,2,6,9-10,12,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the antagonist [3H]spiperone + GTP to label the low affinity stat...				J Med Chem 40: 4235-56 (1998) Article DOI: 10.1021/jm9703653 BindingDB Entry DOI: 10.7270/Q2KP82TD
					More data for this Ligand-Target Pair