BDBM50061697 6-(3,5-Dimethyl-phenylsulfanyl)-1-(2-hydroxy-ethoxymethyl)-5-isopropyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one::CHEMBL274265

SMILES: CC(C)c1c(Sc2cc(C)cc(C)c2)n(COCCO)c(=S)[nH]c1=O

InChI Key: InChIKey=BFWDEZUKKBSUKN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50061697 (6-(3,5-Dimethyl-phenylsulfanyl)-1-(2-hydroxy-ethox...) Show SMILES CC(C)c1c(Sc2cc(C)cc(C)c2)n(COCCO)c(=S)[nH]c1=O Show InChI InChI=1S/C18H24N2O3S2/c1-11(2)15-16(22)19-18(24)20(10-23-6-5-21)17(15)25-14-8-12(3)7-13(4)9-14/h7-9,11,21H,5-6,10H2,1-4H3,(H,19,22,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description Inhibitory concentration against HIV-1 reverse transcriptase				J Med Chem 40: 4257-64 (1998) Article DOI: 10.1021/jm970110p BindingDB Entry DOI: 10.7270/Q2WS8SC3
					More data for this Ligand-Target Pair