BDBM50061706 (1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]-acetonitrile::CHEMBL344892

SMILES: CO\N=C(/C#N)C12CCN(CC1)C2

InChI Key: InChIKey=LRXMLERJAJTUBK-DHZHZOJOSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50061706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50061706 ((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...) Show SMILES CO\N=C(/C#N)C12CCN(CC1)C2 Show InChI InChI=1S/C9H13N3O/c1-13-11-8(6-10)9-2-4-12(7-9)5-3-9/h2-5,7H2,1H3/b11-8+	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro affinity against human Muscarinic acetylcholine receptor M1 using quinuclidynyl benzylate (QNB)				J Med Chem 40: 4265-80 (1998) Article DOI: 10.1021/jm9702903 BindingDB Entry DOI: 10.7270/Q2S46R2D
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50061706 ((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...) Show SMILES CO\N=C(/C#N)C12CCN(CC1)C2 Show InChI InChI=1S/C9H13N3O/c1-13-11-8(6-10)9-2-4-12(7-9)5-3-9/h2-5,7H2,1H3/b11-8+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro affinity of the compound is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor ...				J Med Chem 40: 4265-80 (1998) Article DOI: 10.1021/jm9702903 BindingDB Entry DOI: 10.7270/Q2S46R2D
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50061706 ((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...) Show SMILES CO\N=C(/C#N)C12CCN(CC1)C2 Show InChI InChI=1S/C9H13N3O/c1-13-11-8(6-10)9-2-4-12(7-9)5-3-9/h2-5,7H2,1H3/b11-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibition of [3H]quinuclidinyl benzilate (QNB) binding to muscarinic receptors of rat cerebral cortex				Citation and Details BindingDB Entry DOI: 10.7270/Q2W37ZG7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50061706 ((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...) Show SMILES CO\N=C(/C#N)C12CCN(CC1)C2 Show InChI InChI=1S/C9H13N3O/c1-13-11-8(6-10)9-2-4-12(7-9)5-3-9/h2-5,7H2,1H3/b11-8+	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro affinity of the compound is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor ...				J Med Chem 40: 4265-80 (1998) Article DOI: 10.1021/jm9702903 BindingDB Entry DOI: 10.7270/Q2S46R2D
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50061706 ((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...) Show SMILES CO\N=C(/C#N)C12CCN(CC1)C2 Show InChI InChI=1S/C9H13N3O/c1-13-11-8(6-10)9-2-4-12(7-9)5-3-9/h2-5,7H2,1H3/b11-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibition of oxotremorine-M (OXO-M) binding to muscarinic receptors of rat cerebral cortex				Citation and Details BindingDB Entry DOI: 10.7270/Q2W37ZG7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50061706 ((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...) Show SMILES CO\N=C(/C#N)C12CCN(CC1)C2 Show InChI InChI=1S/C9H13N3O/c1-13-11-8(6-10)9-2-4-12(7-9)5-3-9/h2-5,7H2,1H3/b11-8+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	495	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro affinity of the compound is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor ...				J Med Chem 40: 4265-80 (1998) Article DOI: 10.1021/jm9702903 BindingDB Entry DOI: 10.7270/Q2S46R2D
					More data for this Ligand-Target Pair