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SMILES: COc1ccc(CCC(=O)N2CCC3(CN(C3)[C@@H]3CCc4cc(ccc34)-c3cc(C)ncn3)CC2)c(c1)C(N)=O

InChI Key: InChIKey=DQSTWVNGNJSKPR-GDLZYMKVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061714   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM50061714
PNG
(CHEMBL3394204)
Show SMILES COc1ccc(CCC(=O)N2CCC3(CN(C3)[C@@H]3CCc4cc(ccc34)-c3cc(C)ncn3)CC2)c(c1)C(N)=O |r|
Show InChI InChI=1S/C32H37N5O3/c1-21-15-28(35-20-34-21)24-4-8-26-23(16-24)5-9-29(26)37-18-32(19-37)11-13-36(14-12-32)30(38)10-6-22-3-7-25(40-2)17-27(22)31(33)39/h3-4,7-8,15-17,20,29H,5-6,9-14,18-19H2,1-2H3,(H2,33,39)/t29-/m1/s1
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Similars
Article
PubMed
 139n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]Ghrelin from human GHS-R1a expressed in HEK293 cells after 8 hrs by SPA method

ACS Med Chem Lett 6: 156-61 (2015)


Article DOI: 10.1021/ml500414n
BindingDB Entry DOI: 10.7270/Q2N58P10
More data for this
Ligand-Target Pair