BDBM50061897 (6aR,9aS)-3,5-Dimethyl-5,6a,7,8,9,9a-hexahydro-1-(phenylmethyl)cyclopent[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(1H)-one::CHEMBL343973

SMILES: CN1C2=N[C@@H]3CCC[C@@H]3N2c2c(c(C)nn2Cc2ccccc2)C1=O

InChI Key: InChIKey=YVOOLDONOWRIEB-CABCVRRESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 5A (Bos taurus)	BDBM50061897 ((6aR,9aS)-3,5-Dimethyl-5,6a,7,8,9,9a-hexahydro-1-(...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2c(c(C)nn2Cc2ccccc2)C1=O |t:2| Show InChI InChI=1S/C19H21N5O/c1-12-16-17(23(21-12)11-13-7-4-3-5-8-13)24-15-10-6-9-14(15)20-19(24)22(2)18(16)25/h3-5,7-8,14-15H,6,9-11H2,1-2H3/t14-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 5 from bovine lung				J Med Chem 40: 4372-7 (1998) Article DOI: 10.1021/jm970495b BindingDB Entry DOI: 10.7270/Q2833R45
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50061897 ((6aR,9aS)-3,5-Dimethyl-5,6a,7,8,9,9a-hexahydro-1-(...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2c(c(C)nn2Cc2ccccc2)C1=O |t:2| Show InChI InChI=1S/C19H21N5O/c1-12-16-17(23(21-12)11-13-7-4-3-5-8-13)24-15-10-6-9-14(15)20-19(24)22(2)18(16)25/h3-5,7-8,14-15H,6,9-11H2,1-2H3/t14-,15+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 3 from bovine heart				J Med Chem 40: 4372-7 (1998) Article DOI: 10.1021/jm970495b BindingDB Entry DOI: 10.7270/Q2833R45
					More data for this Ligand-Target Pair