BDBM50061899 2',5'-Dimethyl-3'-(phenylmethyl)spiro[cyclopentane1,7'(8'H)-[2H]imidazol[1,2-a]pyrzolo[4,3-e]pyrimidin]-4'-(5'H)-one::CHEMBL137400

SMILES: CN1C2=NC3(CCCC3)CN2c2nn(C)c(Cc3ccccc3)c2C1=O

InChI Key: InChIKey=FDOVMJSEGUQXQX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061899   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase (Bos taurus)	BDBM50061899 (2',5'-Dimethyl-3'-(phenylmethyl)spiro[cyclopentane...) Show SMILES CN1C2=NC3(CCCC3)CN2c2nn(C)c(Cc3ccccc3)c2C1=O |t:2| Show InChI InChI=1S/C20H23N5O/c1-23-18(26)16-15(12-14-8-4-3-5-9-14)24(2)22-17(16)25-13-20(21-19(23)25)10-6-7-11-20/h3-5,8-9H,6-7,10-13H2,1-2H3	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 3 from bovine heart				J Med Chem 40: 4372-7 (1998) Article DOI: 10.1021/jm970495b BindingDB Entry DOI: 10.7270/Q2833R45
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50061899 (2',5'-Dimethyl-3'-(phenylmethyl)spiro[cyclopentane...) Show SMILES CN1C2=NC3(CCCC3)CN2c2nn(C)c(Cc3ccccc3)c2C1=O |t:2| Show InChI InChI=1S/C20H23N5O/c1-23-18(26)16-15(12-14-8-4-3-5-9-14)24(2)22-17(16)25-13-20(21-19(23)25)10-6-7-11-20/h3-5,8-9H,6-7,10-13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 2 from bovine adrenal cortex				J Med Chem 40: 4372-7 (1998) Article DOI: 10.1021/jm970495b BindingDB Entry DOI: 10.7270/Q2833R45
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50061899 (2',5'-Dimethyl-3'-(phenylmethyl)spiro[cyclopentane...) Show SMILES CN1C2=NC3(CCCC3)CN2c2nn(C)c(Cc3ccccc3)c2C1=O |t:2| Show InChI InChI=1S/C20H23N5O/c1-23-18(26)16-15(12-14-8-4-3-5-9-14)24(2)22-17(16)25-13-20(21-19(23)25)10-6-7-11-20/h3-5,8-9H,6-7,10-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 5 from bovine lung				J Med Chem 40: 4372-7 (1998) Article DOI: 10.1021/jm970495b BindingDB Entry DOI: 10.7270/Q2833R45
					More data for this Ligand-Target Pair