BDBM50061903 3-Benzyl-2,5,7,7-tetramethyl-7,8-dihydro-2H,5H-1,2,5,6,8a-pentaaza-as-indacen-4-one::CHEMBL137712

SMILES: CN1C2=NC(C)(C)CN2c2nn(C)c(Cc3ccccc3)c2C1=O

InChI Key: InChIKey=XZXFCSVKXLUIFK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061903   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50061903 (3-Benzyl-2,5,7,7-tetramethyl-7,8-dihydro-2H,5H-1,2...) Show SMILES CN1C2=NC(C)(C)CN2c2nn(C)c(Cc3ccccc3)c2C1=O |t:2| Show InChI InChI=1S/C18H21N5O/c1-18(2)11-23-15-14(16(24)21(3)17(23)19-18)13(22(4)20-15)10-12-8-6-5-7-9-12/h5-9H,10-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 5 from bovine lung				J Med Chem 40: 4372-7 (1998) Article DOI: 10.1021/jm970495b BindingDB Entry DOI: 10.7270/Q2833R45
					More data for this Ligand-Target Pair
Phosphodiesterase (Bos taurus)	BDBM50061903 (3-Benzyl-2,5,7,7-tetramethyl-7,8-dihydro-2H,5H-1,2...) Show SMILES CN1C2=NC(C)(C)CN2c2nn(C)c(Cc3ccccc3)c2C1=O |t:2| Show InChI InChI=1S/C18H21N5O/c1-18(2)11-23-15-14(16(24)21(3)17(23)19-18)13(22(4)20-15)10-12-8-6-5-7-9-12/h5-9H,10-11H2,1-4H3	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 3 from bovine heart				J Med Chem 40: 4372-7 (1998) Article DOI: 10.1021/jm970495b BindingDB Entry DOI: 10.7270/Q2833R45
					More data for this Ligand-Target Pair